Cell shape regulates global histone acetylation in human mammary epithelial cells
نویسندگان
چکیده
منابع مشابه
Cell shape regulates global histone acetylation in human mammary epithelial cells.
Extracellular matrix (ECM) regulates cell morphology and gene expression in vivo; these relationships are maintained in three-dimensional (3D) cultures of mammary epithelial cells. In the presence of laminin-rich ECM (lrECM), mammary epithelial cells round up and undergo global histone deacetylation, a process critical for their functional differentiation. However, it remains unclear whether lr...
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ژورنال
عنوان ژورنال: Experimental Cell Research
سال: 2007
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2007.04.022